For one, it prevents serotonin from being taken back up into neurons after it is released, which increases the total amount of serotonin available to the brain. In simpler words, this means it has two main effects. Trazodone is a sedative and antidepressant medication belonging to the class of serotonin receptor antagonists and reuptake inhibitors (SARIs). We have written this post for informational purposes only, and our goal is solely to inform people about the science behind trazodone’s effects, mechanisms, and current medical uses. This medication is only approved for the treatment of certain specific medical disorders, and can only be taken by prescription and with oversight from a licensed medical professional. Read on to learn more about the various medical uses, mechanisms, and potential side-effects of this drug.ĭisclaimer: This post is not a recommendation or endorsement for trazodone. It is also sometimes used “off-label” to relieve certain symptoms of bulimia, dementia, and alcoholism. Trazodone is an FDA-approved treatment for depression, anxiety, and some forms of insomnia. A plus sign next to the number “” means that the information is found within the full scientific study rather than the abstract. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at that each number in parentheses is a clickable link to peer-reviewed scientific studies. Our goal is to not have a single piece of inaccurate information on this website. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists.Īll of our content is written by scientists and people with a strong science background. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. We believe that the most accurate information is found directly in the scientific source. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed.
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